Is promethease worth it reddit Promethease is great, and codegen. NutraHacker and Genetic Nah, not really. There's a possibility that the data science team at 23andMe has recently adjusted the raw data. The new report (since they were bought by the Israeli company) Personal opinion: while there are many different companies out there, Promethease is one of the best tools for anyone looking to dig into the specific SNPs (single nucleotide polymorphisms) Is Promethease worth it? Affordability: Promethease is more affordable than similar services, making it accessible to many users. There has been a lot of research on the microbiome's interaction with those diseases. June 28, 2019 - requested sync of data with sequencing. I had uploaded it elsewhere in at least one additional database. However if you do an ancestry test with 23 or ancestry dna you also can upload the raw results to companies like promethease which compare it to their entire research database which will 7. Please post your (ancestry) results Get the Reddit app Scan this QR code to download the app now. I'd say it was worth between $75 and $125, but not the price of $250, especially My main purpose of getting DNA tests is not to track ancestry, but so that I can run the raw data through Promethease and similar sites to generate In addition, Promethease is a "look up table" that looks into public databases to see if there is any information about the meaning of the variant. It's not always easy to tell what the bottom line is. It’s cheap, but is it helpful? Learn about its pros and cons in this Promethease review. The SNPs that are reported in ancestry tests are typically selected because they do the best job of determining ancestry, not because they do the best job of identifying health issues. What I find curious is that Promethease provides everything that is known about certain conditions (both bad and good repute - I presume this means the nature of the result rather than the reputation of the studies) whereas 23andme only provide the negatives. Genes that increase your risk seem like more on paper than they do in real life. Like AncestryDNA Traits, Promethease is also $10 (versus $8 for Gene Heritage). Many have said they never got responses, but they resolved my issue. . It may be worth downloading a fresh raw data file Promethease is great for what medical research says about certain parts of your DNA. Or check it out in the app stores A place for discussing Promethease, a report about your DNA based on the scientific literature cited in SNPedia. Then offer to sell you the whole annotating thing, but wait a few days. Promethease and 23andMe Health Alternative The good news is that Promethease and 23andMe can be complementary services – you can use your raw DNA data from 23andMe to access A 4 magnitude in and of itself should most definitely looked into further and not disregarded. Cardano is a decentralised public blockchain and cryptocurrency project and is fully open source. It’s amazing and you can look into so much more, including the SNPs that Promethease and the others ignore since they’re not known/confirmed mutations. That's really the difference. If you have autism/Asperger's and this is literally your only genetic marker related to it, then that would tell us a really interesting thing: someone can be autistic with barely any genetic influence! Some of the results on Promethease can seem downright scary to the layman. Then you download the Enlis Genome Browser. Totally worth it. You might want to weigh whether you want to know that at all. Is promethease still worth buying or is the information on free websites like codegen enough? I am a huge fan of Promethease for this reason-- it is a cost-effective way to see if there is anything that really warrants discussion with a genetics professional-- I recommend sorting by "Magnitude", and anything rated as 4 or higher might be worth looking at further-- if this is the case for you, then I recommend being very specific when A place for discussing Promethease, a report about your DNA based on the scientific literature cited in SNPedia. I only had 1 "bad" tagged result filtered with a 3 magnitude or higher on Promethease which was: rs1333049(C;C) 1. I found this email on an old reddit thread and they responded within a few days. Reddit users have expressed serious concerns about the validity of Promethease’s commitments to privacy. They have all kinds of health reports and a rarely mentioned feature is you can upload all your blood test results and track them over time with recommendations to get into optimal levels. Is promethease still worth buying or is the information on free websites like codegen enough? Is the insight gained worth the risk of higher insurance costs or possible denial of coverage? I'm torn between the value of preventive care and the financial implications. A full blown test would be worth the money if you suspect you might have a predisposition to certain types of genetic disorders (eg: BRCA1 or BRCA2 mutations for breast cancer). Had a quick Google and it doesn't seem like their paid reports are worth it though. If there's a 0,3% chance for disease x and you have a risk gene that multiplies your risk by 2x, it's still 0,6% and therefore kinda irrelevant. It is not a super useful test yet, but arguably more so than testing your own genes for this. I have results post-FDA-ban, and I'm not sure how the old data compares to Promethease. Gene Heritage, on the other hand, has less traits, but seems better curated, more honest and accurate, and easier to understand. the only useful bit i got was that i’m a rapid metabolizer for the CYP2C19 enzyme, and i have actually been on a few of the medications affected by that, which just didn’t work on me. eu is a free health service that gave similar information as Promethease. I also uploaded my raw data from 23andMe to Gedmatch for their calculations of what I might be genetically; on 23andMe I got 99. It’s not full genome testing. The problem is that we know these databases are wrong ~25% of the time. It shows a lot more information than 23andMe with a In 2015 I used Promethease. One of my favorite quotes is Adam Savage's "If it's worth doing, it's worth overdoing". r/promethease. Get the Reddit app Scan this QR code to download the app now. Cardano is developing a smart contract platform which seeks to deliver more advanced features than any protocol previously developed. My grandmother recently passed at age 80 from complications of this exact thing, but she was a lifelong smoker which may have exacerbated her risk factors. A place for discussing Promethease, a Promethease shows the data provided by you that overlaps with SNPedia, including showing you the normal forms when they are present. A place for discussing Promethease, a report about your DNA based on the scientific literature cited It's concerning to note that earlier 23andMe chips identified this as CC, while newer ones might show it as II. Comprehensive Data: The platform provides detailed Promethease provides a report based on your raw DNA data. CaffeinatedGuy . Promethease is more work. Members Online The genealogy subreddit auto deleted my post and I can't copy/paste the words. I used my 23andMe file on SelfDecode - worth it imo. For me accurately predicted high incidence for Rheumatoid Arthritis and Her+ Breast Cancer. Promethease reports while a lot of data will give you a magnitude report that is quite detailed. Considering current symptoms being similar and a frequency under 1%, in my non medical unprofessional suggestion, I would say you either have it, will have it, or have very similar symptoms shared with Crohn's and that steps should be taken with a medical professional and Get the Reddit app Scan this QR code to download the app now. 9x increased risk for coronary artery disease. The best genetic test for medical purposes depends on your situation:. That has become a life motto for me Anyway, I got the raw data from 23andMe and put it in Promethease and DNA. The conversation about Promethease on Reddit . Thank you so much. com (Dante had not shared data as of July 12, 2019) June 29, 2019 - ordered hard drive with BAM and FASTQ files (Dante had not shipped data as of July 12, 2019) Get the Reddit app Scan this QR code to download the app now. There are some contradictory things in Promethease as well as things that won't apply to you. 23&Me doesn't have these issues, everything connects to you and they make the conclusions for you. I just re-ran my same DNA file to get updated reports. A place for discussing Promethease, a report about your DNA based on the scientific literature cited in I was hoping somebody with knowledge in genetics could answer this for me: Would having the genotype gs194, and also the SNPs- rs1333049(C;C), rs2383206(G;G), rs17602(C;T), rs187238(G;G), rs10757278(G;G), rs6025(A;G), rs1800795(G;G),rs10757272 be worth looking into? These were the main SNPs that brought forth my attention; seeing how they are, or can There are already companies (Genesight is one example) that provide these services using medical grade analysis rather than relying on dtc genetic sequencing data. Trying to use that for diagnostic purposes is circular at best. They’ll email back offering 50% off that. I was going to edit my Tellmegen file but it’s inconsistent on what things are like, scored in a way that is seen as “opposite” in promethease (where you’ll get false positives) and what things are like, straight with SNPedia and stuff. Basically if you have more time than money, do Promethease. a lot of the 1 magnitude SNPs aren't necessarily worth I was wondering if anyone has any input on if it’s worth going for the most expensive kit? The more expensive one is giving you health information. You'll see that in your Promethease report rs587779548(G;G) is outlined in green, which means it's a common/normal/good genotype, and, the summary tells you it's the common form, and, the Repute says "good", and, the magnitude Get the Reddit app Scan this QR code to download the app now. Or check it out in the app stores   A place for discussing Promethease, a report about your DNA based on the scientific literature cited in SNPedia. What was more useful tho was I got promethease, and uploaded my raw data from 23andme. A place for discussing Promethease, a report about your DNA based on the scientific literature cited in SNPedia. For what it's worth, the report I'd been trying to get came through this AM. Or check it out in the app stores what would you recommend doing to get your money's worth and the best useful practical understanding with the data? Hey that's me. Is it worth it to do it again, or would the results pretty much be the same I have a promethease test from 2015, would it be worth rerunning the same data from 23andMe to see what new research appears? Or will it be He recommended I do a 23andMe test while he researched other conditions. I got the health analysis for free because I participated in a study, thankfully, because I definitely would not have paid for it. rs7158782(G;G) 4x higher risk of adverse side-effect if taking aromatase inhibitor rs7158782 is one of 4 SNPs found on chromosome 14 near a gene known as T-cell leukemia/lymphoma 1A ( TCL1A). Carrier for super rare (1:200,000) disorder worth Get the Reddit app Scan this QR code to download the app now. Or check it out in the app stores   It's not worth worrying about, trust me. Myheritage bought them, and now their support is what you need to use. It would certainly be worth mentioning to your Dr. You have one snp that's been identified as having a positive link to autism. Plus, there's always Promethease, although the info on 23andMe tends to be more direct and validated. So, I just got back my Ancestry DNA results. I didn’t have to do any conversations at all. Land. Is that true? So I guess it comes down to whether the extra cost of 23andMe health info on top of Promethease is worth it vs. I have a BRCA test and mammogram concerning a lump next week. 23andme health gives you the FDA approved high effect stuff. Promethease definitely. Promethease gives you everything and the kitchen sink. I worried for maybe a day or two, looked up some stuff online, and that's that. Members Online rs1801181 (t;t) and Ehlers Danlos/sulfur Get the Reddit app Scan this QR code to download the app now. That’s what promethease said with a note it might be more serious with another genes involvement. The expert said it isn’t a straightforward Disease like that and full gene testing would need to be done which I didn’t do. 8% southeast asian but on gedmatch genesis on one of their calculators, I'm 70-80% southeast asian but it really depends on which the information i got was super vague, “you have a typical likelihood of developing etc etc” for almost everything and expectedly so for the price compared to a more in depth service. Reply reply 8K subscribers in the promethease community. How often does Promethease update their data? How often is it worth pulling your results again? I pulled my data about three years ago. 6K subscribers in the promethease community. So it doesn’t test for everything. I’ve been suffering from RA for 6 years. Also in 2019, Reddit users reported that MyHeritage gained access to their raw genetic data from Promethease even after they deleted their information. Or check it out in the app stores   One of the big drawbacks of Promethease (and most genetics-information sites) is that the research informing the analysis is done on Caucasians and/or people of European descent. I think is very worth it. I had started a process where I was If you don't have the extra cash to spare then I'd recommend getting the ancestry test only, downloading your raw DNA data, and then uploading to a website like Promethease that diagnoses health conditions for free (note: it doesn't test for all of the ones that 23andMe does, but it also tests for ones that 23andMe does not show). Some users found that their genetic information had A full blown test would be worth the money if you suspect you might have a predisposition to certain types of genetic disorders (eg: BRCA1 or BRCA2 mutations for breast cancer). just uploading raw data from I need some help understanding my Promethease results. (1:200,000) disorder worth seeing doctor? upvotes r/promethease. I was wondering if it would be worth my money to upload it to promethease, since they test for a lot of Promethease report is less interesting without raw data, too. Is promethease still worth buying or is the information on free We would like to show you a description here but the site won’t allow us. The report showed I have a variant for EDS that 23andme doesn't report on So I was think about just getting 23andMe Health Kit while its on sale so I can have that to compare for Ancestry stuff for family history (compared I think it's important to note that there will be conflicts detected, but these conflicts should be listed by promethease. While I understand that you can upload the 23andMe info to Promethease, I heard that a Promethease report based on Ancestry raw data contains more than twice as many genotypes as 23andMe. No links worked and I could not update the files. Since you have an interest in genetics maybe you should try ubiome's smartgut test. some things i also Get the Reddit app Scan this QR code to download the app now. Is promethease still worth buying or is the information on free websites like codegen enough? You pay promethease a little bit of money and they generate a report based on information in SNPedia. Took four days, but oh well. Carrier for super rare (1:200,000) disorder worth seeing doctor? It turns out I’m a carrier for homocystinuria, which seems Keep in mind that "more SNPs" does not equate to "better health information". I am sorry to hear that. If you find anything worth digging into, make sure that SNP isn't on the conflict list and always reference it against nebula's information to ensure accuracy using this method. bojb tdahd oopl pcl piwc rbkd duivv yzqhe utnadat beyw